Royal Air Force Typhoon jets have operated alongside French aircraft in a coordinated attack against an hidden munitions depot in Syria used by the IS group, per a report from the UK's MoD.
The location, pinpointed through surveillance, was assessed as storing arms and explosives, the statement said, and was situated in hills just north of Palmyra in central Syria.
"Our aircraft used Paveway IV guided bombs to strike a series of entry passages leading to the facility... initial indications indicate the objective was successfully hit," the ministry announced.
There was no indication of any civilian impact in the strike on Saturday evening and each participating jet returned to base without incident, the defence officials confirmed.
The British jets were supported by a Voyager aerial refuelling aircraft.
IS - alternatively referred to as Daesh - established extremist governance over parts of both Syria and Iraq until 2019.
"This strike underscores the UK's leading role, and commitment to stand shoulder to shoulder with our partners, to eradicate any revival of IS and their violent and radical beliefs in the Middle East," Britain's Defence Chief John Healey said.
RAF aircraft have conducted patrols over Syria to "prevent any attempted comeback" of Islamic State after its military defeat at the Baghuz confrontation in the year 2019, the MoD reported.
"I want to thank the personnel of our armed forces involved in this strike for their skill and their courage," he commented. "Including them were numerous UK service members on duty over Christmas and New Year. This action, to eliminate militants who pose a risk to our security, shows how our armed forces are prepared to act, all year round, protecting the UK domestically and strong abroad."
In December, the United States armed forces executed what it described as a "major assault" on IS targets in the country, following an assault killed two US servicemembers and a civilian linguist in the Palmyra area.
The United Nations says Islamic State still has an estimated 5,000 to 7,000 combatants in both countries.
